Identification of Clostridium difficile ribotype 027 for the first time in Mainland China.

نویسندگان

  • Pu Wang
  • Youlian Zhou
  • Zhongqiu Wang
  • Shan Xie
  • Ting Zhang
  • Minyi Lin
  • Runhua Li
  • Jiasheng Tan
  • Ye Chen
  • Bo Jiang
چکیده

was 1.60 (95% confidence interval [CI], 1.02-2.51), P = .04. 2. Of those subjects who received a PPI and vancomycin alone, the relapse rate was 28.0% (7/25), compared to 10.3% (8/78) in those who received vancomycin alone and no PPI. The unadjusted OR was 3.40 (95% CI, 1.0910.63), P = .05. 3. Of those who received any treatment (metronidazole or vancomycin or both) and a PPI, the relapse rate was 33.8% (68/201), compared to 21.7% (123/568) for those who did not receive a PPI. The unadjusted OR was 1.85 (95% CI, 1.30-2.64), P<.01. 4. Of those patients who received both metronidazole and vancomycin as well as a PPI, the relapse rate was 42.9% (21/49), compared to 26.2% (37/141) for those who received both agents but not a PPI. The unadjusted OR was 2.11 (95% CI, 1.07-4.16), P = .03.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The First Two Clostridium difficile Ribotype 027/ST1 Isolates Identified in Beijing, China–an Emerging Problem or a Neglected Threat?

Clostridium difficile hyper-virulent ribotype 027 strain has become a significant concern globally, but has rarely been reported in Asian countries including China. Recently, a retrospective single-center study in Beijing, China, detected two ribotype 027 C. difficile isolates from two patients coming for outpatient visits in 2012 and 2013. We performed a systematic investigation of the two iso...

متن کامل

Efficacy of three surface disinfectants against spores of Clostridium difficile ribotype 027.

BACKGROUND The emergence of Clostridium difficile ribotype 027 raised the question of sporicidal surface disinfectants are also effective against spores of C. difficile ribotype 027. MATERIALS AND METHODS Three surface disinfectants based on magnesium monoperoxyphthalate hexahydrate (Dismozon pur), a combination of (ethylenedioxy)dimethanol, glutaral and benzyl-C12-18-alkyldimethylammonium ch...

متن کامل

Molecular epidemiology of clostridium difficile in a tertiary medical center in Israel: emergence of the polymerase chain reaction ribotype 027.

BACKGROUND The rate of infection with Clostridium difficile colitis and its associated mortality have been increasing in the last decade. The molecular epidemiology of C. difficile in Israel has not been studied. OBJECTIVES To screen for the existence of the 027 and 078 ribotypes and determine the longitudinal molecular epidemiology of the circulating clinical C. difficile isolates in a large...

متن کامل

Clostridium difficile Ribotype 027, Toxinotype III, the Netherlands

Outbreaks due to Clostridium difficile polymerase chain reaction (PCR) ribotype 027, toxinotype III, were detected in 7 hospitals in the Netherlands from April 2005 to February 2006. One hospital experienced at the same time a second outbreak due to a toxin A-negative C. difficile PCR ribotype 017 toxinotype VIII strain. The outbreaks are difficult to control.

متن کامل

The First Case of Antibiotic-associated Colitis by Clostridium difficile PCR Ribotype 027 in Korea

Clostridium difficile (C. difficile) is a common causative agent of pseudomembranous colitis (PMC). C. difficile-associated diarrhea (CDAD) ranges from mild diarrhea to life threatening PMC. Recently, a highly virulent strain of C. difficile polymerase chain reaction ribotype 027 was found in North America, Europe, and Japan. A 52-yr-old woman with anti-tuberculosis medication and neurogenic bl...

متن کامل

Identification of Clostridium difficile Ribotype 027 for the First Time in Mainland China

was 1.60 (95% confidence interval [CI], 1.02-2.51), P = .04. 2. Of those subjects who received a PPI and vancomycin alone, the relapse rate was 28.0% (7/25), compared to 10.3% (8/78) in those who received vancomycin alone and no PPI. The unadjusted OR was 3.40 (95% CI, 1.0910.63), P = .05. 3. Of those who received any treatment (metronidazole or vancomycin or both) and a PPI, the relapse rate w...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Infection control and hospital epidemiology

دوره 35 1  شماره 

صفحات  -

تاریخ انتشار 2014